Preparation of nanoparticles from acrylated palm oil microemulsion using radiation technique
Abstract
ABSTRACT
The use of microemulsion in the development of nanoparticle based on acrylated palm oil product is demonstrated. Acrylated palm oil microemulsions were prepared using ionic surfactant. Combination methods of emulsion polymerization and radiation crosslinking were applied to the microemulsion system for synthesizing nanoparticle. The ionizing radiation technique was introduced to generate a crosslinking reaction in the development of nanoparticle. The nanoparticle was evaluated in terms of particle diameter, surface charge, pH and conductance. Their image was captured using Transmission electron microscopy (TEM). Results show that the size, charge and shape of the particles are influenced by concentration of surfactants, monomer concentration, radiation dose and time of storage. The study showed a promising method to produced nanoparticle. This nano-sized product has the potential to be utilized as controlled-drug-release-carrier.
ABSTRAK
Kajian ke atas pembangunan produk nanopartikel menggunakan sistem mickroemulsi berasaskan minyak sawit berakrilat telah dijalankan. Sistem mikroemulsi minyak sawit berakrilat telah dihasilkan daripada surfaktan ionik. Gabungan teknik pempolimeran emulsi dan taut-silang melalui sinaran telah diaplikasikan ke atas sistem mikroemulsi untuk mensintesis partikel nano. Teknik sinaran mengion digunakan untuk tindak balas taut-silang dalam pembangunan partikel nano. Pencirian partikel nano telah dilakukan dari segi diameter partikel, cas permukaan, pH dan konduktans. Imej partikel telah digambarkan menggunakan kaedah mikroskop transmisi elektron (TEM). Hasil kajian menunjukkan saiz, cas dan bentuk partikel nano adalah dipengaruhi oleh kepekatan surfaktan, kepekatan monomer, dos sinaran dan tempoh penyimpanan. Hasil kajian ini menunjukkan teknik penghasilan partikel bersaiz nano telah dibangunkan dan produk ini berpontesi untuk digunapakai sebagai agen pelepasan ubat terkawal.